At the end of this module, the student should be able to:
1. Diagnose the cause and distinguish a lower GI bleed from an upper GI bleed
2. Outline the physiologic response to acute massive lower GI bleed
3. Propose medical or surgical management plan for lower GI bleed
4. Advise patient for diagnostic and management options to GI bleed
5. Describe and perform appropriate procedure like NGT insertion and rectal examination
I. WORKING PROBLEM STRAND
To achieve the terminal objectives, the students should know the:
A. Biological Perspective
Anatomy of the Lower GI from the ligament of Treitz to anus ( Gross and Microscopic)
Trace vascular Supply of the lower GI
Outline of the physiologic response to massive GI bleeding
Time required for fluid shift in response to GI bleed
Role and limitation for measurement of hemoglobin and Hematocrit in acute GI bleeding
Physiologic estimation of blood loss
Immunologic basis for blood typing
Guaiac stool test for occult blood – biochemical basis
List the important cause of GI bleeding and their respective mechanism for bleeding
Inflammatory bowels syndrome
Infectious colitis – amoebic colitis
Pitfalls in the microsocpic diagnosis of amoebiasis
Anti-amoebic drugs – pharmacokinetics and indications
Use of fresh frozen plasma
Antibiotics role in diverticulitis
Outline the emergency management of patient with massive
Understand how the patient is prepared for and monitored during blood transfusion
State the indication for transfusion of uncross-matched
blood and blood type utilized if the patients
blood type is unknown
Tilt Test- significance , indication and contraindication
Diagnostic approach to diagnosis of LGI bleed
Barium Enema – double air contrast
Arteriography – angiography
Treatment options and the choice of haemostatic modality
Surgical treatment criteria ( indication for surgery)
High fiber diet role
B. Behavioral Perspective
Medico-ethical issues on emergency blood transfusion
Understanding the feelings of patient as regards to diagnostic procedure ( their fear and anxiety )
II. PROFESSIONAL SKILL STRAND
Indications for NGT insertion
Indication for rectal examination
Procedural steps for NGT insertion
Choice of appropriate size of NGT
III. COMMUNITY STRAND
Population at risk for Lower GI bleeding
Community Health plan for the control of amoebic colitis in the community
Mrs. Tomasa Calabasa ., 69 y.o., female, retired nurse from Lustre, Z.C., consulted because of hematoschezia.
|1. What is her problem?
2. What is hematochezia?
List your hypothesis as to the cause and suggest a mechanism by which the hypothesis can lead to the presenting problem.
3. What additional information do you need from Mrs. C.?
Questions for the tutor:
Sample questions for tutors to use as prompts:
1. What questions do you want to ask Mrs. C. regarding her problem? Why are you asking these questions?
2. What are the anatomical structures involved in bleeding in the intestinal tract?
3. What is the significance of the color of the blood?
What is the difference between melena and tarry stools?
Maroon colored stools?
4. What does the rate of bleeding have to do with the color of the stools or is it the length of the bowel in relation to transit time? How about transit time?
5. Discuss the possible causes – mechanism of bleeding in the following entities:
Infection/inflammation – shigellosis, amoebiasis, colitis
Parasitic infestations – pinworms
Anal and rectal lesions – hemorrhoids, fissures
Colonic lesions – angiodysplasia, polyps, cancer
1. Different diseases causing bleeding from the lower GI.
2. Clinical differentiation between UGIB and LGIB
3. Clinical Manifestations
4. Etiopathogenesis of GIB
Her condition was noted a few hours prior to admission when the patient complained of hematochezia of three episodes amounting to a cupful per episode. There was no alteration in urination. There was no cough, chest pain nor fever.
The patient was admitted to a private hospital about a year ago because of lower GI bleeding and several times at another hospital because of essential hypertension.
There is a history of diabetes in the family. The patient denies smoking nor drinking alcoholic beverages.
There was no recent intake of any medications.
1. Lead the students to reformulate their earlier hypothesis based on the new information.
2. Why did you reformulate your hypothesis that way?
3. What other information would you require at this time?
Potential Learning issues to cover
1. Significance of the amount of bleeding? Frequency of bleeding
2. Effect of bleeding on the patient.. hemodynamically..
3. What is the significance of the history of bleeding episode before?
4. Is the hypertension a risk factor?
5. Systemic versus local cause of bleeding?
Prompts to help students inter-connect learning issues from other modules with this case.
1. Risk factor for bleeding from the gastrointestinal tract.
2. Hypertension and vascular accidents (SMA thrombosis… intestinal angina.. ischemia)
The physical examination of the patient:
Elderly female, undernourished, conscious, coherent, ambulatory not
in distress with the following vital signs:
BP = 180/100 HR = 80/min RR = 22/min
Head and Neck : pinkish palpebral conjunctiva
Chest : clear breath sounds: (-) crackles
Heart : regular rate and rhythm; no murmurs
Abdomen flat, soft, (-) organomegaly
Rectal Exam : good tone; (-) tenderness, (+) blood on the examining
finger: no external
hemorrhoids; no masses
1. Ask students to review and re-rank hypothesis in the light of new information from the P.E.
2. Discuss ano-rectal lesions which can be seen and palpated.
3. Discuss how they would like to work this patient up if they were the attending physician.
4. Change scenario to a massive bleeding episode with hypotension, tachycardia .. pallor
Review the resuscitative measures for a patient with lower GI bleeding.
Correlate issues learned in ther modules like shock due to hemorrhage, or burns.
When is the bleeding considered massive? Assessment of blood loss.
Review replacement and maintenance of blood volume.
When do we call in the surgeon?
Why do we have to call a surgeon?
What about endoscopist?
Paraclinical diagnostic procedures
Indications, accuracy, complications
The following laboratories were ordered by the admitting physician:
CBC, CT, BT, blood typing, platelet count
ECG 12 leads
FBS, creatinine, uric acid, cholesterol, triglycerides
The patient was hooked with an IV fluid and blood was requested.
Medications given included:
Nifedipine 5 mg. SL
Tranexamic acid 500 mg IVTT now then 500 mg capsule 3 x a day
Orders for monitoring the amount and frequency of hematochezia.
On referral to the department of surgery on the same day, the following laboratories were ordered:
Barium enema – Show the X-ray plates of this patient
Prompt the student to interpret it
Review with them how to identify Colon from Intestines
|Questions for Tutors:
1. Comment on the paraclinicals ordered. Suggest a rationale for each.
2. What would you have done in this case?
3. What is tranexamic acid? Its action and side effects, if any.
1. Rational use of paraclinicals tests
Occult blood in stools, significance.
Specificity and accuracy of such test. e.g. false negative
2. Action, indications and side effects of tranexamic acid and other hemostatic agents.
CBC FBS = 4.0
Hgb 8 BUN = 7
Hct 24 Creatinine = 80
WBC 5000 x 10 Uric acid = 220
neutrophils .60 Cholesterol = NA
lymphocytes.20 Triglycerides = NA
Chest x-ray : Atheromatous aorta
residual lung fibrosis
Barium enema ; Multiple diverticulosis with occasional signs of spasticity.
Incidentally pelvic cavity calcification. Merits ultrasound correlation.
(plates available for viewing at the deans office). Request the students to rationalize how air-contrast media radiology is achieved and its rationale.
Ultrasound, pelvis : Uterus is small measuring 4.6 x 2.2 x 1.7 c and is normal with the age of the patient. Endometrial stripe is intact.
No adnexal mass seen.
Impression ; Normal uterus and adnexa.
ECG : within normal limits
|Prompts for the Tutors:
1. Review the case. Ask the student to make a brief summary of the case, or an algorithm.
2. Give feedback on their summary( if they are focused, brief and concise.)
3. Ask them to interpret the lab. results and how it helped them in their impression of the case so far.
4. Inquire students on the modality of treatment for this patient. Are there other options? Advantages and disadvantages of one option over the other in terms of risks and complications.
5. How would they advise this patient regarding treatment. How would you treat the anemia here?
6. If the diverticulitis were not that extensive, would the treatment approach differ?
7. Why did this patient have no abdominal pain symptoms in the past considering she has a very extensive multiple diverticulosis?
8. Does diverticulosis aftect digestion and absorption of nutrients?
9. What is the relationship between diverticulosis and the intestinal gut flora?
10. Why was a pelvic examination/ultrasound done here? was it indicated?
1. Rational, logical approach to a diagnosis – diverticulosis
2. Advice about treatment and treatment modalities.
3. Etiopathology of diverticulitis. How do they come about?
4. Complications of diverticulosis
The patient underwent exploratory laparotomy with resection of the descending colon, tranverse colon and the distal descending colon with primary anastomosis. The calcification in the pelvis turned out to be serosal myomas which were excised.
The patient had a stormy postoperative course but eventually improved and was discharged well. The patient is now still alive and doing well.
Post operatively. what complications do you antecepate after surgery?
e.g. Vit B12 absorption and others.
Can this surgical resection affect fat digestion and absorption postoperatively?
How would you care for the nutrition of this patient?
Trigger 6 : Behavioral and Population Perspective
1. This experience of seeing blood in the stools is very frightening to the patient . Even more so the fact to be told that she has to undergo resection of the entire colon practically.
What possible concern do you think the patient has? How can you help her verbalize these?
How would you address these concerns?
How far should you go to support this patient?
What is the limit of your role?
2. How common is GIT bleeding? Which group of population are susceptible to this syndrome? Why?
3. Are there any risk factors that you can think of that may be forerunners to GIT bleeding ? Health habits or behavior? How would you address them?