The Office of the Vice President for Administration (VPA) ensures the smooth, efficient, and safe operations of Ateneo de Zamboanga University. It oversees vital administrative units such as the Center for Information Technology Services (CITS), Physical Plant Office (PPO), Purchasing and Custodian Office (PCO), University Security Office (USO), University Safety Office, University Infirmary, University Archives, and the Lantaka Campus Administration.

In addition, the VPA Office supervises campus services including the canteens, dormitory facilities, and other support operations that sustain the daily needs of the university community.